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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
26.06
Human Site:
T461
Identified Species:
44.1
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
T461
S
V
L
I
A
Q
Q
T
D
T
S
D
P
E
K
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
T461
S
V
L
I
A
Q
Q
T
D
T
S
D
P
E
K
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
T515
S
M
L
I
A
Q
Q
T
D
T
S
D
P
E
K
Dog
Lupus familis
XP_538355
1323
142434
T461
S
V
L
I
A
Q
Q
T
D
T
S
D
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
T463
S
V
L
I
V
Q
Q
T
D
T
S
D
P
E
K
Rat
Rattus norvegicus
NP_001012199
431
46388
A310
C
E
I
K
R
D
A
A
L
V
V
A
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
T463
P
V
L
I
T
Q
Q
T
D
T
S
D
P
E
K
Chicken
Gallus gallus
NP_001006237
580
63057
T454
S
V
L
I
A
Q
Q
T
D
T
S
D
V
E
K
Frog
Xenopus laevis
O13066
580
62889
V454
S
A
M
I
A
Q
Q
V
N
V
A
D
T
E
K
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
V439
S
V
L
I
Q
Q
Q
V
D
V
L
D
V
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
P464
K
F
C
L
S
Q
K
P
C
S
Q
E
D
F
D
Honey Bee
Apis mellifera
XP_395378
580
63771
D438
A
K
N
S
S
N
S
D
S
S
S
E
L
K
F
Nematode Worm
Caenorhab. elegans
P34342
960
105635
L620
F
I
A
G
R
N
R
L
E
N
P
G
A
H
A
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
V266
K
N
L
N
K
L
E
V
I
N
F
G
D
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
93.3
100
N.A.
93.3
0
N.A.
86.6
93.3
53.3
60
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
86.6
93.3
73.3
60
N.A.
40
40
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
43
0
8
8
0
0
8
8
8
8
8
% A
% Cys:
8
0
8
0
0
0
0
0
8
0
0
0
0
15
0
% C
% Asp:
0
0
0
0
0
8
0
8
58
0
0
65
15
0
8
% D
% Glu:
0
8
0
0
0
0
8
0
8
0
0
15
8
58
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
8
65
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
15
8
0
8
8
0
8
0
0
0
0
0
0
8
65
% K
% Leu:
0
0
65
8
0
8
0
8
8
0
8
0
8
0
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
15
0
0
8
15
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
8
0
43
0
0
% P
% Gln:
0
0
0
0
8
72
65
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
15
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
58
0
0
8
15
0
8
0
8
15
58
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
50
0
50
0
0
8
0
0
% T
% Val:
0
50
0
0
8
0
0
22
0
22
8
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _